Introduction – Context of the study The landscape of genomic research is vast and evolving, with a significant focus on understanding how genetic variations contribute to functional differences in genes and subsequent phenotypic expressions. Among the plethora of genetic variations, single nucleotide polymorphisms (SNPs) stand out due to their prevalence and potential impact on human […]
Tag: Genetic loci
Unveiling the Impact of Cryptic Relatedness: Decoding Genetic Confounders in Case-Control Association Studies
Introduction – Context of the Study In the realm of human genetics, case-control association studies serve as a cornerstone for identifying genetic variants linked to various human diseases. These studies entail comparing individuals with a particular condition (cases) to those without it (controls) to discern any genetic differences. However, a significant challenge undermines the reliability […]