Pain’s Secret Sabotage: How Chronic Pancreatitis Pain Affects the Mind

Introduction Imagine waking up each day to an invisible shadow that affects not just how you feel physically but also how well your brain functions. This isn’t the latest science fiction plot; it’s the reality for many living with chronic pain from conditions like pancreatitis. Chronic pancreatitis isn’t just an assault on the body—it infiltrates […]

Neuroanatomical Correlates of Suicide in Psychosis: The Possible Role of von Economo Neurons

Neurons, Emotions, and the Enigma of Suicide Neurons, Emotions, and the Enigma of Suicide Introduction The human brain is a labyrinth of mysteries, each twist and turn revealing secrets of our innermost thoughts and feelings. Among the myriad of questions that haunt us, one stands starkly at the forefront: Why do some individuals in the […]

The Silent Influence: How Publication Bias Skews Our Understanding of Placebo and Treatment Effects

Introduction: Peeking Behind the Curtain of Clinical Trials Imagine this: you’re at a magic show, eagerly anticipating the illusionist’s grand finale. As the curtain rises, you’re left in awe, not just because of the trick itself, but due to the careful orchestration behind it. Now, switch settings to the field of medical research where clinical […]

Deciphering the Genetic Code of Gut Discomfort: How COMT Polymorphism Shapes Irritable Bowel Syndrome

Introduction: The Genetic Puzzle Behind Gut Feelings Imagine feeling anxious about your meeting at work and subsequently experiencing an uncomfortable gloomy day, while being unable to pinpoint the trigger. Many people live with this enigma as an ever-looming shadow known as Irritable Bowel Syndrome (IBS). Characterized by symptoms such as regular abdominal pain and irregular […]

The Intricate Dance Between Genes and Pain: Understanding Thermal Perception and the Mysteries of the Mind

Introduction: Pain, Genes, and Our Psyche – A Tangled Web Imagine touching a hot stove and not flinching or feeling the sting of an icy wind without a shiver. The way we perceive thermal pain—those scorching heats and numbing colds—is not merely a physical response but a complex interaction deeply rooted in our biology. This […]